Research – Mycotoxins in Food: Cancer Risks and Strategies for Control

MDPI

Abstract

Mycotoxins are toxic compounds produced by fungi such as AspergillusPenicillium, and Fusarium, contaminating various food crops and posing severe risks to food safety and human health. This review discusses mycotoxins‘ origins, significance, and impact, particularly in relation to cancer risk. Major mycotoxins like aflatoxins, ochratoxins, fumonisins, zearalenone, and patulin are examined, along with their sources and affected foods. The carcinogenic mechanisms of these toxins, including their biochemical and molecular interactions, are explored, as well as epidemiological evidence linking mycotoxin exposure to cancer in high-risk populations. The review also highlights critical methodologies for mycotoxin detection, including HPLC, GC-MS, MS, and ELISA, and the sample preparation techniques critical for accurate analysis. Strategies for controlling mycotoxin contamination, both pre- and post-harvest, are discussed, along with regulations from organizations like the FAO and WHO. Current challenges in detection sensitivity, cost, and control effectiveness are noted. Future research is needed to develop innovative analytical techniques, improve control strategies, and address the influence of climate change on mycotoxin production. Finally, global collaboration and emerging technologies are essential for advancing mycotoxin control and enhancing food safety.

Research – Estimating Underdetection of Foodborne Disease Outbreaks

CDC

To the Editor: In the February issue, Ford et al. used the power law to estimate underdetection of foodborne disease outbreaks in the United States (1). Two of their main conclusions are entirely reasonable: small outbreaks are more likely to go undetected than large outbreaks, and the use of whole-genome sequencing (WGS) has improved the detection of small outbreaks caused by pathogens for which WGS is used. However, their conclusion on the usefulness of the power law itself needs further consideration.

Ford et al. analyzed the size of all foodborne outbreaks reported to the national Foodborne Disease Outbreak Surveillance System during 1998–2019. They defined outbreak size as the number of laboratory-confirmed cases. However, laboratory-confirmed cases are only good estimators for the size of outbreaks detected through pathogen-specific surveillance, such as for Salmonella, where outbreak detection follows the accumulation of confirmed cases. For outbreaks associated with events or establishments, identification might rely on reports from consumers, many of whom do not seek healthcare; thus, stool specimens might only be collected from a few cases to confirm the etiology. Consumer complaints are the primary means for identifying foodborne outbreaks caused by norovirus. The Council to Improve Foodborne Outbreak Response recommends collecting clinical specimens from >5 members from the ill group in such settings (2). Thus, the number of confirmed cases in an outbreak is dependent on how the outbreak is detected. Outbreaks detected by complaint generally have few confirmed cases, even though they can involve large numbers of illnesses.

To provide a fair evaluation for the usefulness of the power law, it may be better to restrict analyses to outbreaks with common detection pathways. For outbreaks detected by pathogen-specific surveillance, counting confirmed cases seems appropriate. For outbreaks detected through consumer complaints, analyses should include all outbreak-associated illnesses.

Research – UK food microbiology lab reports updates on recent work

Food Safety News

The main food microbiology lab in the United Kingdom has shared highlights of its recent activity in an annual report.

The report covers work of the UK’s national reference laboratory (NRL) for food microbiology between April 2023 and March 2024.

The UK Health Security Agency (UKHSA) provides the service for the Food Standards Agency (FSA) and Food Standards Scotland (FSS). It covers Listeria monocytogenes, coagulase-positive staphylococci, E. coli, Campylobacter, Salmonella, and antimicrobial resistance.

Research – Outbreak of Listeriosis Likely Associated with Baker’s Yeast Products, Switzerland, 2022–2024

CDC

Abstract

We traced back a nationwide outbreak of human listeriosis in Switzerland to a persisting production line contamination of a factory producing baker’s yeast with Listeria monocytogenes serotype 1/2a sequence type 3141. We used whole-genome sequencing to match clinical isolates to isolates from product samples.

Research – Effects of Combined Cold Plasma and Organic Acid-Based Sanitizer Treatments Against Salmonella enterica on Tomato Surfaces

Wiley Online

ABSTRACT

Incidence of foodborne illness due to bacterial contamination of fresh produce continue to exist despite continuous research on processing interventions to mitigate the problem. In this study, we combined atmospheric cold plasma treatments with an antimicrobial solution containing specific organic acids generally recognized as safe (GRAS) by the FDA and tested its antimicrobial efficacy against Salmonella enterica inoculated on tomato surfaces. Tomato surfaces were inoculated with at 5.6 log CFU/g of Salmonella by spotting 0.1 mL of 7 log CFU/ml Salmonella onto the tomato stem scars, and by dipping whole tomatoes into a solution of 7 log CFU/ml Salmonella for 3 min to achieve 4.1 log CFU/g. Antimicrobial efficacy of the organic acid-based sanitizer + cold plasma treatments for 30, 60, 120, 180, and 360 s, were investigated, and significant bacterial inactivation was achieved above 120 s treatments. At 120 s, surviving populations of aerobic mesophilic bacteria recovered on the tomatoes surfaces averaged < 2 logs/g while yeast and mold survival averaged < 1 CFU/g. Treatment combination with this organic acid-based sanitizer + cold plasma for 120 s resulted in a 4.9 log reduction of Salmonella on the stem scar area and a 3.9 log reduction on the smooth peel surface. Similarly, populations of aerobic mesophilic bacteria recovered on treated tomato surfaces averaged < 0.3 log CFU/g. The results of this study indicate that combining an organic acid-based sanitizer with cold plasma treatments for ≥ 120 s can inactivates significant populations of Salmonella to enhance the microbial safety of tomato surfaces designated for fresh-cut salad.

Denmark – Yeast growth in snack sausages

Foedevarestyrelsen

Hanegal A/S is recalling the snack sausages Salami Stick and Beef Stick, as yeast growth has been found in the products. The yeast growth can discolor the snack sausages and give them a sour, off-flavor that makes them unsuitable as food.

If you have the products, you should discard them or return them to the store where you bought them.

Picture of the snack sausages
Image of the products

Which food is recalled

Chicken Salami Stick, 25g

EAN no: 5709760003775

Best before dates: 10/12/2024; 12.12.2024; 18.12.2024; 25.12.2024 and 01.01.2025

Rooster Beef Stick, 25g

EAN no: 5709760003782

Best-before dates: 04.12.2024; 12.12.2024; 18.12.2024; 25.12.2024 and 01.01.2025

Where is the product sold

The product is sold in:  Rema1000, Føtex, Bilka, Netto, Meny, Coop365, Kvickly, Brugsen, Dagli’Brugsen and in SuperBrugsen stores throughout the country and on http://www.nemlig.com.

Why is the product being recalled?

There is a risk of yeast growth in the products. Fermentation in products can cause them to appear discolored and with a sour and deviant taste. The snack sausages are therefore unsuitable as food.

Read more on the Danish Veterinary and Food Administration’s website about spoilage bacteria, yeasts and molds by clicking on the link here.

What should you do as a consumer?

The Danish Veterinary and Food Administration advises consumers to discard the products or return them to the store where they were purchased. 

Who recalls the product

Hanegal A/S

Finlandsvej 12

6100 Haderslev

Iceland – E. coli O145 confirmed in children and mixed mince

MAST

Foodborne infection has been confirmed at the Mánagardı nursery school in Reykjavík. The causative agent is E. coli bacteria of a type known as STEC and of serotype O145. Analysis of samples at Matís confirmed that the same serotype, i.e. E. coli O145 was found both in faecal samples from children from the kindergarten and in a sample of minced meat used in cooking at the kindergarten. Their sequencing of the bacteria’s genetic material showed that the origin is the same.

After detailed interviews with the parents of the children, who fell ill, attention soon turned to Thursday, October 17 last. The Reykjavík Health Authority went to the site and took numerous samples for analysis of the food used in the cooking that day, such as minced meat, vegetables, lentils, melons, oatmeal and more. All food samples were negative for E. coli except for the mince. A few children who normally do not eat meat also fell ill, but it is not possible to confirm the route of infection for them. They may have been infected by other children who attended the kindergarten after they got sick but before the kindergarten was closed.

The mince turned out to be mixed beef and sheep mince from Kjarnaföð. It did not go on general sale, but only sold to larger kitchens, such as restaurants, canteens and kindergartens. Matvælastofnun contacted the representatives of the company when suspicion was directed at the mince, and the same day the company contacted all parties who received mince from the same production batch that was used in the Mánagard nursery school. During the recall, it was found that buyers had already used it in their operations. There have been no reports of infection or sickness among consumers at other kitchens.

E. coli bacteria are part of the natural intestinal flora of humans and animals and can be introduced into water, meat, vegetables and other foods during their production. Different types of E. coli exist. Most types of E. coli are harmless, but Shigatoxin-producing E. coli (STEC) carry genes that encode toxins that can cause illness (virulence genes). However, their strains can be highly pathogenic.

According to legislation on meat production, producers are not required to ensure that all meat is free of E. coli before it goes to market. However, meat producers should do everything in their power to reduce the chance of contamination of carcasses and meat products in the process. It is primarily done with clean grips, proper hand techniques and clean equipment. Sampling in the process is therefore aimed at checking whether working methods are adequate. The Food Agency reported on a screening of the presence of pathogenic bacteria in Icelandic meat on the Icelandic market in 2018. It stated that STEC virulence genes were found in almost 30% of lamb samples and 11.5% of beef samples.

Cleanliness and proper handling of meat and adequate cooking by users/consumers is therefore key to preventing infection caused by E. coli , including STEC from meat. The steering group’s research has revealed that the handling of the minced meat in this respect during cooking in the kindergarten was insufficient.

It is common practice that beef, lamb and horse steaks are served without being deep-fried. Raw cuts of meat have bacteria on the surface of the meat but not inside the muscle. They are therefore killed when the meat is fried or grilled at high temperatures. Hamburgers and other dishes made from minced meat are different, because during the mincing process, microorganisms spread throughout the mince. Insufficient heating/frying does not kill bacteria present deep inside the mince. In order to kill E. coli and other disease-causing microorganisms, hamburgers and other mincemeat dishes must be fried through or so that the core temperature is at least 75°C.

France – FQC Raw Milk Cheese Platter 520G AND FQC Raw Milk Ossau Iraty – Listeria monocytogenes

RASFF

Product Category
Food
Product subcategory
Milk and dairy products
Product brand name
FQC (Carrefour Quality Line)
Model names or references
– Farandole of raw milk cheeses (cheese platter) – Ossau Iraty made with raw milk
Product identification
GTIN Batch Date
3560071070137 415 Expiry date 03/11/2024
3560071070137 423 Expiry date 08/11/2024
3560071070137 425 Expiry date 10/11/2024
3560071070137 441 Expiry date 11/19/2024
3560071070137 441 Expiry date 11/17/2024
3245415890250 138421 Expiry date 06/11/2024
3245415890250 138424 Expiry date 09/11/2024
3245415875752 132413 Expiry date 01/11/2024
3245415875752 138423 Expiry date 08/11/2024
Packaging
– Farandole of raw milk cheeses (cheese platter): 520 g – Ossau Iraty made from raw milk: Free weight
Start/End of marketing date
From 10/12/2024 to 10/31/2024
Storage temperature
Product to be kept in the refrigerator
Health mark
FR 63 113 081 CE
Geographic area of ​​sale
Whole France
Distributors
Crossroads

RASFF Alerts – Salmonella – Polish Poultry Products – Chicken Neck Skins – Minced Beef – Rucola – Red Cabbage – Chicken Wings – Salami – Pasteurised Egg Products – Rocket Salad – Sesame Paste – Broiler Chickens

RASFF

Salmonella Typhimurium detected in minced beef from Sweden in Poland

RASFF

Salmonella Enteritidis in egg white crystals from the Netherlands in Belgium

RASFF

Salmonella spp. from group “C” in poultry meat from Poland in Lithuania and France

RASFF

Salmonella agona in turkey meat from Poland in Italy

RASFF

Salmonella on neck skins from France in Luxembourg

RASFF

The presence of Salmonella spp. bacteria was found in 3 out of 5 samples tested in 25 g of the product called Chicken kebab. Whole chicken (raw deep-frozen meat product) originating from Poland in the Czech Republic

RASFF

Salmonella spp. in turkey medallions from Poland in the Czech Republic

RASFF

Salmonella enterica subsp. Livingstone in rucola from Italy in Slovenia

RASFF

Salmonella Enteritidis in fresh fillets of broiler chickens from Poland in Lithuania

RASFF

Salmonella Infantis in fresh wings of broiler chickens from Poland in Lithuania

RASFF

Presence of Salmonella spp. in sprouts of Brassica oleracea (red cabbage) from Spain, with raw material from Italy

RASFF

Detected Salmonella in rucola from Italy in Sweden

RASFF

Salmonella Typhimurium in chilled turkey meat from Poland in the Czech Republic

RASFF

Salmonella Infantis in chicken wings from Austria in Germany

RASFF

Salmonella Typhimurium in neck skins from France in Belgium, Latvia and Luxembourg

RASFF

Salmonella Coeln in frozen fillets of broiler chickens from Ukraine in Lithuania and Denmark

RASFF

Recall of Duck Products in Iceland Due to Salmonella from Poland in Iceland and Denmark

RASFF

Salmonella spp in Salami/meat product from Italy in Netherlands and Austria

RASFF

Salmonella spp in pasteurized egg products from Spain in Portugal

RASFF

Salmonella enteritides in poultry meat from Poland in Netherlands and Germany

RASFF

Salmonella spp. in rocket salad from Italy from Italy in Germany

RASFF

Salmonella Colindale in sesame paste from Türkiye in Germany, Netherlands and UK

RASFF Alert- Mold/Mould – Tortilla Wraps

RASFF

Mold on Vegan Tortilla Wraps from the Netherlands in Italy, Bulgaria and Belgium