McMaster researchers have developed a novel new gel made entirely from bacteria-killing viruses.
The anti-bacterial gel, which can be targeted to attack specific forms of bacteria, holds promise for numerous beneficial applications in medicine and environmental protection.
Among many possibilities, it could be used as an antibacterial coating for implants and artificial joints, as a sterile growth scaffold for human tissue, or in environmental cleanup operations, says chemical engineer Zeinab Hosseini-Doust.
Her lab, which specializes in developing engineering solutions for infectious disease, grew, extracted and packed together so many of the viruses — called bacteriophages, or simply phages — that they assembled themselves spontaneously into liquid crystals and, with the help of a chemical binder, formed into a gelatin-like substance that can heal itself when cut.
Lowering mutation rates in harmful bacteria might be an as yet untried way to hinder the emergence of antimicrobial pathogens. One target for drug development might be a protein factor, DNA translocase Mfd, that enables bacteria to evolve rapidly by promoting mutations in many different bacterial species. This action speeds antibiotic resistance, including multi-drug resistance. Working on drugs to block Mfd and similar factors could be a revolutionary strategy to address the worldwide crisis of treatment-resistant infectious diseases
Posted in Antibiotic Resistance, Antimicrobials, Bacteria, bacterial contamination, Bacterial Infections, drug resistant, food contamination, food death, Food Illness, Food Micro Blog, Food Microbiology Blog, Food Pathogen, Food Poisoning, Uncategorized
Outbreak News Today
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Norwegian health authorities are warning people who are particularly vulnerable to Vibrio infections to take precautions while swimming as a number of serious bacterial infections ave been recorded.
This summer, six people have been severely ill with wound infection due to bacteria in seawater (five Vibrio and one Shewanella). The infection has occurred after swimming in the Oslo Fjord.
All adults over the age of 50 who have had a sore wound or have suffered sores during bathing in the Oslo Fjord in five different municipalities, Bærum, Oslo, Moss, Vestby and Fredrikstad.
In addition to the serious cases we know from earlier, there have been reports of 20 people who have had mild Vibrio infections on August 8th. These are sore infections and ear infections that often do not require treatment.