Category Archives: Hepatitis A

USA – FDA Core Investigation Table Update – Investigations of Foodborne Illness Outbreaks

FDA

What’s New

  • For the outbreak of hepatitis A virus (ref #1143), cases have increased from 7 to 8. This change has been made on the advisory for this outbreak.
  • A new investigation has been added to the table (ref#1152). Although the pathogen/cause of illness and products linked to illnesses is not yet identified, there are 13 illnesses from one state linked to a single restaurant that has suspended operations. FDA has initiated traceback in coordination with state partners.
Date
Posted
Ref Pathogen
or
Cause of
Illness
Product(s)
Linked to
Illnesses

(if any)
Total
Case
Count

Status
4/26/2023 1152 Not Yet Identified Not Yet
Identified
13 Active
3/29/2023 1141 Salmonella Infantis Raw Flour See
CDC
Investigation
Notice
Active
3/1/2023 1143 Hepatitis A Virus Frozen Organic
Strawberries
See
Outbreak
Advisory
Active
2/15/2023 1123 Listeria
monocytogenes
Not Yet
Identified
See
CDC
Investigation
Notice
Active

USA – CDC Update – Multistate Outbreak of Hepatitis A Virus Infections Linked to Frozen Organic Strawberries

cdc

  • Reported cases: 8
  • States: 2
  • Hospitalizations: 2
  • Deaths: 0
  • As of April 21, 2023, there are:
    • 8 outbreak-associated cases of hepatitis A reported from 2 states (California and Washington).
    • Illnesses started on dates ranging from November 24, 2022, to April 12, 2023.
    • 2 people have been hospitalized. No deaths have been reported.
  • Epidemiologic and traceback evidence indicate that frozen organic strawberries are the likely source of this outbreak.
    • In interviews, 8/8 (100%) people reported eating frozen organic strawberries.

USA- FDA Core Outbreak Table Update – Investigations of Foodborne Illness Outbreaks

FDA

What’s New

  • For the outbreak of Salmonella Infantis (ref #1141), an onsite inspection and sample collection and analysis has been initiated.
  • For the outbreak of Salmonella Hartford (ref #1144), the case count has increased from 53 to 54 cases. This outbreak has ended and the investigation has closed, with no vehicle identified.
  • For the outbreak of hepatitis A virus (ref #1143), an onsite inspection has been initiated.
Date
Posted
Ref Pathogen
or
Cause of
Illness
Product(s)
Linked to
Illnesses

(if any)
Total
Case
Count

Status
3/29/2023 1141 Salmonella Infantis Raw Flour See
CDC
Investigation
Notice
Active
3/1/2023 1143 Hepatitis A Virus Frozen Organic
Strawberries
See
Outbreak
Advisory
Active
2/15/2023 1123 Listeria
monocytogenes
Not Yet
Identified
See
CDC
Investigation
Notice
Active

USA – FDA says the hepatitis A virus in this year’s frozen strawberry outbreak is identical to one from 2022

Food Safety News

Federal officials have confirmed that the strain of hepatitis A virus found in frozen organic strawberries involved in a multi-state outbreak this year is the same strain that caused an outbreak in 2022.

The organic strawberries associated with both outbreaks were imported to the United States from the same growing area in Baja California, Mexico, according to an outbreak update from the U.S. Food and Drug Administration.

So far this year there have been seven people confirmed infected and all seven reported eating frozen organic strawberries. Two of the patients required hospitalization.

FDA’s traceback investigation identified a common supplier of frozen organic strawberries, but Tuesday’s update did not name the supplier. Both this year and in 2022 the implicated strawberries were sold at a variety of stores under several different brand names.

USA – FDA – Core Outbreak Table – Update

FDA

What’s New

  • On 4/11/2023, an updated outbreak advisory was issued for the outbreak of hepatitis A virus linked to frozen organic strawberries (reference #1143).
  • The outbreak of Listeria monocytogenes (ref #1127) linked to enoki mushrooms has ended and the FDA investigation is closed.
Date
Posted
Ref Pathogen
or
Cause of
Illness
Product(s)
Linked to
Illnesses

(if any)
Total
Case
Count

Status
3/29/2023 1141 Salmonella Infantis Raw Flour See
CDC
Investigation
Notice
Active
3/8/2023 1144 Salmonella Hartford Not Yet
Identified
53 Active
3/1/2023 1143 Hepatitis A Virus Frozen Organic
Strawberries
See
Outbreak
Advisory
Active
2/15/2023 1123 Listeria
monocytogenes
Not Yet
Identified
See
CDC
Investigation
Notice
Active

Research – How to deal with food poisoning while traveling—and how to avoid it altogether

National Geographic

Some countries have a reputation for putting travelers at a higher risk for gastrointestinal illnesses. But you can get sick from an improperly handled meal anywhere in the world.

Pad thai from a Bangkok street vendor or raw milk cheese from a bistro in France taste delicious in the moment. But for many travelers, the local dishes that make trips meaningful sometimes give them food poisoning—and the wrong sort of vacation memories.

By some metrics, gastrointestinal infections related to food or water affect 30 to 70 percent of all travelers during or immediately after their trips, according to a 2015 study in BMJ Clinical Evidence. Each year, one in six Americans and nearly one in 10 people worldwide suffer from such illnesses caused by bacteria (E. coli, salmonella, listeria), viruses (norovirus, hepatitis A), or parasites (giardiasis, roundworms, tapeworms).

Lower-income countries have a reputation for putting travelers at a higher risk for food poisoning, but people are just as likely to be sickened from an improperly handled meal in Italy or Australia—or from some sushi at their local supermarket.

Here’s why people get food poisoning, what to do if it strikes, and how to (maybe) prevent it, read at the link above.

USA – Update – Outbreak Investigation of Hepatitis A Virus Infections: Frozen Strawberries (February 2023)

FDA

Product

California Splendor Recall: Kirkland Signature 4-lb. bag Frozen Organic Whole Strawberries in certain states with specific lot codes.

Scenic Fruit Recall: frozen organic strawberries with the following brand names and Best By Dates distributed to specific states:

  • Simply Nature, Organic Strawberries, Best By 06/14/2024
  • Vital Choice, Organic Strawberries, BEST BY 05/20/2024
  • Kirkland Signature, Organic Strawberries, Best If Used By 10/08/2024
  • Made With, Organic Strawberries, Best Before 11/20/2024
  • PCC Community Markets, Organic Strawberries, Best By 29/10/2024
  • Trader Joe’s, Organic Tropical Fruit Blend with the following Best By dates: 04/25/24; 05/12/24; 05/23/24; 05/30/24; 06/07/24

Stores Affected

California Splendor supplied recalled product to Costco stores in Los Angeles and Hawaii, and to two San Diego business centers. Scenic Fruit supplied recalled product to Costco, Aldi, KeHE, Vital Choice Seafood, and PCC Community Markets in specific states, and to Trader Joe’s nationwide.

On March 17, 2023, the retailer, Meijer, also issued press to voluntarily recall Made-WithExternal Link Disclaimer brand frozen organic strawberries from certain market store locations.

This is not an exhaustive list of products or stores. FDA is continuing to work with the firms to identify potential additional product information.

Symptoms of Hepatitis A

Illness usually occurs within 15 to 50 days after eating or drinking contaminated food or water. Symptoms of hepatitis A virus infection include fatigue, nausea, vomiting, abdominal pain, jaundice, dark urine, and pale stool. In some instances, particularly in children under the age of six, hepatitis A infection may be asymptomatic.

Status

Ongoing

Recommendation

  • Consumers, restaurants, and retailers should not sell, serve, or eat recalled frozen strawberries. These recalled products should be returned or thrown away.
  • If consumers purchased the recalled frozen organic strawberries and ate those berries in the last two weeks, and have not been vaccinated against hepatitis A, they should immediately consult with their healthcare professional to determine whether post exposure prophylaxis (PEP) is needed. PEP is recommended for unvaccinated people who have been exposed to hepatitis A virus in the last two weeks because vaccination can prevent a hepatitis A virus infection if given within 14 days of exposure. Those with evidence of previous hepatitis A vaccination or previous hepatitis A virus infection do not require PEP.
  • Contact your healthcare provider if you think you may have symptoms of a hepatitis A virus infection after eating these frozen organic strawberries, or if you believe that you have eaten these strawberries in the last two weeks.

Current Update

April 11, 2023

The FDA and CDC, in collaboration with state and local partners, are investigating an outbreak of hepatitis A virus infections linked to frozen organic strawberries imported by a common supplier from certain farms located in Baja California, Mexico. The frozen organic strawberries were sold to a variety of retailers under multiple brand labels.

Based on epidemiological data collected by CDC, 7/7 (100%) people who provided information about what they ate before becoming ill reported eating frozen organic strawberries. FDA’s traceback investigation identified a common supplier of the frozen organic strawberries. Strawberries used by this supplier were imported from certain farms located in Baja California, Mexico, in 2022. Additionally, the strain of hepatitis A virus causing illnesses this year is genetically identical to the strain that caused the outbreak of hepatitis A virus infections in 2022, which was linked to fresh organic strawberries imported from Baja California, Mexico, and sold at various retailers.


Case Counts

Total Illnesses: 7
Hospitalizations: 2
Deaths: 0
Last Illness Onset: March 26, 2023
States with Cases: WA (5), CA (2)
Product Distribution: Nationwide

USA – FDA – Core Outbreak Table – Investigations of Foodborne Illness Outbreaks

FDA

Date
Posted
Ref Pathogen
or
Cause of
Illness
Product(s)
Linked to
Illnesses

(if any)
Total
Case
Count

Status
3/29/2023 1141 Salmonella Infantis Raw Flour See
CDC
Investigation
Notice
Active
3/8/2023 1144 Salmonella Hartford Not Yet
Identified
53 Active
3/1/2023 1143 Hepatitis A Virus Frozen Organic
Strawberries
See
Outbreak
Advisory
Active
2/15/2023 1123 Listeria
monocytogenes
Not Yet
Identified
See
CDC
Investigation
Notice
Active
11/9/2022 1127 Listeria
monocytogenes
Enoki
Mushrooms
See
Outbreak
Advisory
Active

Research – Rare Recombinant GI.5[P4] Norovirus That Caused a Large Foodborne Outbreak of Gastroenteritis in a Hotel in Spain in 2021 – Food Handler

Journals ASM

Noroviruses are among the most important causes of acute gastroenteritis (AGE). In summer 2021, a large outbreak of norovirus infections affecting 163 patients, including 15 norovirus-confirmed food handlers, occurred in a hotel in Murcia in southeast Spain. A rare GI.5[P4] norovirus strain was identified as the cause of the outbreak.
The epidemiological investigation determined that norovirus transmission might have been initiated through an infected food handler. The food safety inspection found that some symptomatic food handlers continued working during illness. Molecular investigation with whole-genome and ORF1 sequencing provided enhanced genetic discrimination over ORF2 sequencing alone and enabled differentiation of the GI.5[P4] strains into separate subclusters, suggesting different chains of transmission. These recombinant viruses have been identified circulating globally over the last 5 years, warranting further global surveillance.
IMPORTANCE Due to the large genetic diversity of noroviruses, it is important to enhance the discriminatory power of typing techniques to differentiate strains when investigating outbreaks and elucidating transmission chains. This study highlights the importance of (i) using whole-genome sequencing to ensure genetic differentiation of GI noroviruses to track chains of transmission during outbreak investigations and (ii) the adherence of symptomatic food handlers to work exclusion rules and strict hand hygiene practices. To our knowledge, this study provides the first full-length genome sequences of GI.5[P4] strains apart from the prototype strain.

USA – FDA Core Investigation Table Update

FDA

What’s New

  • A new outbreak of Salmonella Infantis (ref #1141) linked to a not yet identified product has been added to the table. FDA has initiated traceback. This investigation is ongoing and additional information will be provided as it becomes available.
  • For the Salmonella Hartford outbreak in a not yet identified food, the case count has increased from 50 to 53 cases.
Date
Posted
Ref Pathogen
or
Cause of
Illness
Product(s)
Linked to
Illnesses

(if any)
Total
Case
Count

Status
3/29/2023 1141 Salmonella Infantis Not Yet
Identified
12 Active
3/8/2023 1144 Salmonella Hartford Not Yet
Identified
53 Active
3/1/2023 1143 Hepatitis A Virus Frozen Organic
Strawberries
See
Outbreak
Advisory
Active
2/15/2023 1123 Listeria
monocytogenes
Not Yet
Identified
See
CDC
Investigation
Notice
Active
11/9/2022 1127 Listeria
monocytogenes
Enoki
Mushrooms
See
Outbreak
Advisory
Active