Category Archives: okadaic acid

 Italy – Heart clams (Cerastoderma spp) – Okadaic Acid Algal – DSP

Salute

Brand : Cooperativa Pescatori Arborea

Name : Heart clams (Cerastoderma spp)

Reason for reporting : Recall due to chemical risk

Publication date : 8 June 2024

Documentation

Documentation

Italy – Local clams (Ruditapes decussatus) – Algal Biotoxin – Okadaic Acid – DSP

Salute

Brand : Cooperativa Pescatori Arborea)

Name : Local clams (Ruditapes decussatus)

Reason for reporting : Recall due to chemical risk

Publication date : 8 June 2024

Documentation

Documentation

Hong Kong – Food Safety Bulletin 95th Issue

CFS

Feature Article

Shellfish Poisoning

The Centre for Food Safety (CFS) received in April 2023 a referral from the Centre for Health Protection of a suspected case of diarrhoetic shellfish poisoning in which the affected persons developed diarrhoea, nausea, vomiting and abdominal pain within an hour after consuming venus clams at a restaurant.  This article gives a brief introduction on shellfish poisoning.

What is Shellfish Poisoning?

Shellfish poisoning is caused by shellfish toxins produced by certain species of algae.  When shellfish eat toxin-producing algae, the toxins can accumulate in their tissue.  Consumption of shellfish containing shellfish toxins by humans can cause a variety of gastrointestinal and neurological illnesses, known as shellfish poisoning.  Examples of shellfish that have been involved in shellfish poisoning include mussels, clams, oysters, scallops and geoducks.

Numerous shellfish toxins have been discovered around the world; they could cause different types of shellfish poisoning.  Five major types of shellfish poisoning are discussed below:

(i) Paralytic shellfish poisoning (PSP) — caused by paralytic shellfish toxins (PSTs), which are a group of water-soluble alkaloid neurotoxins, including saxitoxins (STXs).

(ii) Diarrhoetic shellfish poisoning (DSP) — caused by diarrhoetic shellfish toxins (DSTs), which are a group of lipid-soluble polyether toxins, including okadaic acid (OA).

(iii) Neurotoxic shellfish poisoning (NSP) — caused by neurotoxic shellfish toxins (NSTs), which are a group of lipid-soluble polyether toxins, including brevetoxins (BTXs).

(iv) Amnesic shellfish poisoning (ASP) — caused by amnesic shellfish toxins (ASTs), including the water-soluble amino acid domoic acid (DA).

(v) Azaspiracid shellfish poisoning (AZP) — caused by azaspiracid shellfish toxins (AZTs), including the lipid-soluble toxin azaspiracid (AZA).

Characteristics of Shellfish Toxins

Different groups of shellfish toxins display multifarious chemical structures, which can be broadly classified into amino acids (DA), alkaloids (STXs) and polyketides (OA, BTXs and AZA).

The reasons why some algae produce shellfish toxins remain unknown.  These toxins are secondary metabolites with no explicit function for the algae.  They are probably used by the algae to compete for space, defence against predators or prevent the overgrowth of other organisms.

In general, shellfish toxins are heat stable, odourless, tasteless and not destroyed by cooking, freezing or other food preparation procedures.  It is hard to distinguish between toxic and non-toxic shellfish visually.

Bioaccumulation of Shellfish Toxins in Bivalve Molluscs

Algae are part of the natural diet of bivalve molluscs.  After shellfish has ingested shellfish toxin-producing algae, shellfish toxins will accumulate and concentrate in their internal organs, such as hepatopancreas of bivalves (Figure 1).  Generally speaking, the adductor muscle contains only a low level of shellfish toxins.

Figure 1: Internal parts of a scallop

Symptoms of Shellfish Poisoning

Shellfish toxins can cause a wide variety of symptoms in humans, depending on the type and amount of toxins ingested.  Symptoms of different types of shellfish poisoning are summarised below:

Safety Levels of Shellfish Toxins

The toxicity of various shellfish toxins was evaluated by a joint expert working group of the Food and Agriculture Organization of the United Nations (FAO), the World Health Organization (WHO) and the Intergovernmental Oceanographic Commission of UNESCO in 2004.  Acute reference doses (ARfDs) (i.e. the amount of toxins that can be ingested in a period of 24 hours or less without appreciable health risk) have been established for these shellfish toxins.  In addition, the Codex Alimentarius Commission (Codex) has established the maximum levels (MLs) for shellfish toxins in edible parts (the whole or any part intended to be eaten separately) of live bivalve molluscs.  While the ARfDs are critical in assessing the safety of food in terms of the level of shellfish toxins contained, Codex MLs are the levels recommended by Codex to be permitted in shellfish.

*An estimate of toxicity of the toxin made by mouse bioassay.

Key Points to Note

  • Shellfish toxins are heat stable, odourless, tasteless and not destroyed by cooking, freezing or other food preparation procedures.
  • It is hard to distinguish between toxic and non-toxic shellfish visually.
  • In general, shellfish toxins accumulate and concentrate in the internal organs of bivalves. 

Advice to Consumers 

  • Purchase shellfish from reliable sources.
  • To reduce the health risk of shellfish poisoning, remove and discard all internal organs of shellfish where possible before consumption.
  • Seek medical attention immediately if you feel ill after eating shellfish.

RASFF Alert- Shellfish Biotoxin – Okadaic Acid Dinophysis Toxin – DSP – Clams

RASFF

Elevated levels of okadaic acid and dinophysis toxin in coquinas from Portugal in Spain

RASFF Alert – Algal Toxin – Okadaic Acid – DSP – Diarrhoeic Shellfish Poisoning

RASFF

Okadaic acid in Diarrhoetic Shellfish Poisoning from Portugal in Spain

RASFF Alerts – Mycotoxin – Okadaic Acid -Mussels

RASFF

Okadaic acid in mussels (Mytilus galloprovincialis) from Spain

Hong Kong – CFS urges public not to consume a kind of chilled razor clams imported from Scotland suspected to be contaminated with lipophilic marine biotoxins

CFS

The Centre for Food Safety (CFS) of the Food and Environmental Hygiene Department today (October 4) urged the public not to consume a kind of chilled razor clams imported from Scotland due to possible contamination with lipophilic marine biotoxins. The trade should stop using or selling the product concerned if they possess it.

Details of the product are as follows:

Product name: Razor Clams
Brand: Lochleven Shellfish
Place of origin: Scotland
Importer: Longfine Seafood Trading Company Limited

A spokesman for the CFS said, “The CFS received a notification from the authorities concerned in Scotland through the International Food Safety Authorities Network (INFOSAN) that the above-mentioned product might have been contaminated with lipophilic marine biotoxins. According to the information provided by INFOSAN, the affected product has been imported into Hong Kong. Upon learning of the incident, the CFS immediately contacted the local importer concerned for follow-up.”

A preliminary investigation found that the above-mentioned importer had imported some of the affected product into Hong Kong. For the sake of prudence, the CFS has instructed the importer to stop sale and remove from shelves the affected batch of product and initiate a recall. Enquiries about the recall can be made to the importer’s hotline at 2387 2388 during office hours.

“Lipophilic marine biotoxins are a group of fat-soluble shellfish poisoning toxins which may cause symptoms such as diarrhoea, nausea and vomiting. In general, they are heat-stable and cannot be destroyed by cooking.” the spokesman said.

The spokesman urged consumers not to consume the affected product if they have bought any. The trade should also stop using or selling the product concerned immediately if they possess it.

The CFS will alert the trade to the incident, continue to follow up and take appropriate action. An investigation is ongoing.

RASFF Alert – LIPOPHILIC BIOTOXINS – LIVE SLIPPER CLAM (VENERUPIS CORRUGATA)

RASFF

HIGH LEVELS OF LIPOPHILIC BIOTOXINS IN LIVE SLIPPER CLAM (VENERUPIS CORRUGATA) FROM PORTUGAL in Spain

RASFF Alert – Marine Biotoxin – Live Slipper Clams

RASFF

HIGH LEVELS OF LIPOPHILIC BIOTOXINS IN LIVE SLIPPER CLAM (VENERUPIS CORRUGATA) FROM PORTUGAL in Spain

Lipophilic marine biotoxins include okadaic acid, pectenotoxin, yessotoxin and azaspiracid groups.

RASFF Alert – DSP – Diarrhetic Shellfish Poisoning – Frozen Stuffed Mussels

RASFF

Diarrhetic Shellfish Poisoning (DSP) toxins (okadaic acid : 293,6 μg/kg) in frozen stuffed mussels(Mytilus galloprovincialis) from Turkey in Greece