Category Archives: E.coli O145

UK E. coli O145 Outbreak hits 256 sick

Food Poison Journal

As of 18 June, there have been a further 45 cases associated with the recent outbreak of STEC O145 since the last update (14 June), bringing the total number of confirmed cases to 256 in the UK. All currently confirmed cases had symptom onset dates before 31 May. Although the rate of cases has now slowed, we expect the figure to rise as NHS laboratories refer specimens to UKHSA for genomic sequencing which can link cases to this outbreak strain.

Confirmed case totals:

  • 168 in England
  • 56 in Scotland
  • 29 in Wales
  • 3 in Northern Ireland (evidence suggests that they acquired their infection in England)

Based on information from 227 cases to date, 38% were admitted to hospital.

Investigations have highlighted pre-packaged sandwich products containing lettuce as the likely source of the outbreak.

UK – Aldi – PRODUCT RECALL – CHICKEN FAJITA TRIPLE WRAP

ALDI

Please note that the following Emergency Withdrawal and Public Product Recall has taken place due to the possible presence of E-coli. 

Product Details: Chicken Fajita Triple Wrap
Brand: Eat and Go
Product Weight: 300g
Bar code: 4088600063577
Best Before Date: 14-16 June
Regions Affected: ALL UK regions

What is Aldi doing about it?
We have removed these products from sale in our store and are recalling all affected products.

What e-mail/phone number can customers contact should they have any questions or problems?
Please click here or call 0800 042 0800.

UKSHA – E. coli advice issued amid rise in cases.

Gov UK

As of 11 June, there have been a further 98 cases associated with this outbreak of STEC O145 in the UK, bringing the total number of confirmed cases to 211. All cases had sample dates before 31 May, but we expect this figure to rise as whole genome sequencing is ongoing to find any further cases which may be linked to the outbreak.

  • 147 in England
  • 27 in Wales
  • 35 in Scotland
  • 2 in Northern Ireland (for these cases, evidence suggests that they acquired their infection while visiting England)

Based on information from 160 cases to date, 42% were admitted to hospital.

UKHSA has worked closely with the Food Standards Agency (FSA), Food Standards Scotland and the devolved public health agencies to investigate the incident, carrying out epidemiological investigations and whole genome sequence analysis to help identify foods commonly consumed by the cases.

As a result of evidence gathered to date, product recall information notices have been published by FSA as a precaution.

Trish Mannes, Incident Director at UKHSA, said:

We would like to thank all the cases who have provided information that has enabled us, through epidemiological analysis of questionnaire data and food tracing investigations, to narrow down the likely food product linked to this outbreak.

Symptoms of infections with STEC include severe and sometimes bloody diarrhoea, stomach cramps, vomiting and fever. If you are unwell, have eaten salad leaves recently and are concerned about any symptoms, follow NHS.uk guidance on when to seek help and the steps you can take to avoid further spread to family and friends.

While diarrhoea and vomiting can have a range of causes, there are simple steps you can take to reduce your risk and risk of infecting others. Washing your hands with soap and warm water and using disinfectants to clean surfaces will help stop any further spread of infection. If you are unwell with diarrhoea and vomiting, you should not prepare food for others while unwell and avoid visiting people in hospitals or care homes to avoid passing on the infection in these settings. Do not return to work, school or nursery until 48 hours after your symptoms have stopped.

Darren Whitby, Head of Incidents at the FSA, said:

Sandwich manufacturers are taking a precautionary measure to recall various sandwiches, wraps, subs and rolls in response to findings from investigations by the Food Standards Agency (FSA), Food Standards Scotland (FSS) and UK Health Security Agency (UKHSA) who are working to identify the cause of an ongoing outbreak caused by shiga toxin-producing E.coli (STEC). The full list of products can be found in the product recall information notice (PRIN).

This is a complex investigation, and we have worked swiftly with the relevant businesses and the local authorities concerned to narrow down the wide range of foods consumed to a small number of salad leaf products that have been used in sandwiches, wraps, subs and rolls. Following thorough food chain analysis, these products are being recalled as a precaution.

Infections caused by STEC bacteria can cause severe bloody diarrhoea and, in some cases, more serious complications. We therefore advise any consumers who have any of these products not to eat them.

The FSA is here to ensure that food is safe. If there are products on the market that are not, we won’t hesitate to take action to remove them.

UK – More than 100 sick in UK E. coli outbreak

Food Safety News

Public health agencies across the United Kingdom are searching for the source of an E. coli outbreak that has sickened more than 100 people in less than two weeks.

There have been 113 confirmed cases in the Shiga toxin-producing E. coli (STEC) O145 outbreak since May 25.

The UK Health Security Agency (UKHSA), Public Health Scotland, and Public Health Wales are investigating the rise in infections.

There is no connection with the E. coli O145 outbreak reported earlier this year, which was linked to raw milk cheese produced by Mrs Kirkham’s that sickened people in England and Scotland.

UK – STEC E-coli advice issued amid rise in cases

Gov UK

The UK Health Security Agency (UKHSA), together with public health agencies in Scotland, Northern Ireland and Wales, are investigating an increase in the number of Shiga toxin-producing Escherichia coli (STEC) cases in the UK in recent weeks.

Infections caused by STEC bacteria can cause severe bloody diarrhoea and, in some cases, more serious complications. It is often transmitted by eating contaminated food but can also be spread by close contact with an infected person, as well as direct contact with an infected animal or its environment.

Whole genome sequencing of samples in the current investigation indicates that most cases are part of a single outbreak. Based on the wide geographic spread of cases, it is most likely that this outbreak is linked to a nationally distributed food item or multiple food items. The source of this outbreak is not yet confirmed but there is currently no evidence linking the outbreak to open farms, drinking water or swimming in contaminated seawater, lakes or rivers. The public health agencies are working with the Food Standards Agency (FSA) and Food Standards Scotland to investigate further.

As of 4 June, there have been 113 confirmed cases associated with this outbreak of STEC O145 in the UK, all reported since 25 May 2024:

  • 81 in England
  • 18 in Wales
  • 13 in Scotland
  • 1 in Northern Ireland (for this case, evidence suggests that they acquired their infection while visiting England)

Typically, we see around 1,500 cases of STEC over a full year. Numbers of confirmed cases associated with this outbreak are expected to rise as further samples undergo whole genome sequencing.

Cases range in age from 2 years old to 79 years old, with the majority of cases in young adults. Of the 81 cases identified to date in England, 61 have provided information to UKHSA related to food, travel and potential exposures and of these we know that 61% have been hospitalised.

While the source of this outbreak is currently unknown, there are steps you can take to reduce your risk of gastrointestinal infections, as well as limiting the spread to others:

  • regularly wash your hands with warm water and soap — alcohol gels do not kill all bugs that cause diarrhoeal illness
  • follow food hygiene measures such as washing fruit and vegetables and cooking food properly
  • if you have diarrhoea and vomiting, you should not prepare food for others and avoid visiting people in hospitals or care homes to avoid passing on the infection
  • you should not return to work, school or nursery until 48 hours after your symptoms have stopped

Trish Mannes, Incident Director at UKHSA, said:

Symptoms of infections with STEC include severe and sometimes bloody diarrhoea, stomach cramps, vomiting and fever. If you have diarrhoea and vomiting, you can take steps to avoid passing it on to family and friends. NHS.UK has information on what to do if you have symptoms and when to seek medical advice.

Washing your hands with soap and warm water and using disinfectants to clean surfaces will help stop infections from spreading. If you are unwell with diarrhoea and vomiting, you should not prepare food for others and avoid visiting people in hospitals or care homes to avoid passing on the infection in these settings. Do not return to work, school or nursery until 48 hours after your symptoms have stopped.

Darren Whitby, Head of Incidents and Resilience at the FSA, said:

The FSA is working with UKHSA and relevant Public Health bodies to identify the source of the illness, which is likely to be linked to one or more food items.

We always advise consumers and those looking after vulnerable people to ensure good hygiene practices are followed when handling and preparing food, regularly washing hands with soap and warm water and ensuring equipment, utensils and surfaces foods come into contact with are cleaned thoroughly to prevent cross contamination.

You should not prepare food for others if you have had symptoms, or for 48 hours after symptoms stop. You can find more information about good hygiene practises – 4c’s, and E. coli on our website.

Jim McMenamin, Head of Health Protection (infection Services), Public Health Scotland, said:

To help stop infections like E. coli from spreading, we advise regular hand washing using soap and water, particularly after using the toilet and before preparing food. People should also use disinfectants to clean surfaces that may be contaminated. Anyone experiencing severe and sometimes bloody diarrhoea, stomach cramps, vomiting and fever should call their GP or 111 to seek advice. Anyone with diarrhoea or vomiting should avoid attending places such as schools, workplaces or social gatherings until at least 48 hours after their symptoms have ceased.

Wendi Shepherd, Consultant in Health Protection for Public Health Wales, said:

Public Health Wales is working with partners in the UK and across the Welsh NHS to investigate this incident. There are currently 18 cases identified in Wales and healthcare providers have been advised of the increase in cases. We would advise anyone who has experienced bloody diarrhoea or severe stomach cramps to seek medical attention.

RASFF Alert – STEC E.coli 026 – 0145- Beef Tartare

 RASFF

Detection of Shigatoxin Escharichia coli (STEC) O26 and O145 in beef tartare from Poland in the UK and Netherlands

UK – Update on reporting of non-O157 STEC infections and an outbreak of Shiga toxin-producing E. coli (STEC) O145 in the UK, February 2024

Gov UK

In December 2023 the UK Health Security Agency (UKHSA) reported (1) unseasonably high levels of Shiga toxin-producing Escherichia coli other than serogroup O157 (non-O157 STEC) case notifications during October to December of that year. Since then, reporting has returned to levels comparable with previous years. Investigations into the drivers of that unseasonal increase in reports of non-O157 STEC continue, as well as into individual outbreaks of STEC that were reported in the December 2023 report.

The investigations into the concurrent foodborne STEC O145: H28 outbreak associated with unpasteurised cheese – being undertaken by UKHSA, the Local Authority (LA) Environmental Health Team, Public Health Scotland (PHS), Food Standards Agency (FSA), Food Standards Scotland (FSS) and the Animal Plant Health Agency (APHA) – are nearly completed.

In total 36 confirmed cases and 1 probable case have been reported across England (n=29) and Scotland (n=8) since late July 2023, with most cases falling ill in November 2023. The last reported primary case had a symptom onset date of 23 December 2023 (see figure below).

Based on epidemiological, food chain and microbiological investigations, the vehicle was identified as an unpasteurised cheese produced in North West England. The food business concerned carried out a product withdrawal and recall on 24 December 2023 (2) and updated on 27 December 2023 (3) which ensured all recalled products were removed from sale in a timely manner.

Subsequent work between the food business, the LA Environmental Health team and the FSA allowed refinement of the product withdrawal and recall notice to include only the batches likely associated with illness, which resulted in a further update of the product withdrawal and recall by the food business on 9 February 2024 (4).

The FSA and FSS both published updated Product Recall Information Notices (PRIN’s) on 24 (2) and 27 December (3), and again on 9 February (4), with supporting news stories to amplify messaging about each of the product recalls.

Research – Genomic surveillance of STEC/EHEC infections in Germany 2020 to 2022 permits insight into virulence gene profiles and novel O-antigen gene clusters

Science Direct

Abstract

Shiga toxin-producing E. coli (STEC), including the subgroup of enterohemorrhagic E. coli (EHEC), are important bacterial pathogens which cause diarrhea and the severe clinical manifestation hemolytic uremic syndrome (HUS). Genomic surveillance of STEC/EHEC is a state-of-the-art tool to identify infection clusters and to extract markers of circulating clinical strains, such as their virulence and resistance profile for risk assessment and implementation of infection prevention measures. The aim of the study was characterization of the clinical STEC population in Germany for establishment of a reference data set. To that end, from 2020 to 2022 1257 STEC isolates, including 39 of known HUS association, were analyzed and lead to a classification of 30.4 % into 129 infection clusters. Major serogroups in all clinical STEC analyzed were O26, O146, O91, O157, O103, and O145; and in HUS-associated strains were O26, O145, O157, O111, and O80. stx1 was less frequently and stx2 or a combination of stx, eaeA and ehxA were more frequently found in HUS-associated strains. Predominant stx gene subtypes in all STEC strains were stx1a (24 %) and stx2a (21 %) and in HUS-associated strains were mainly stx2a (69 %) and the combination of stx1a and stx2a (12.8 %). Furthermore, two novel O-antigen gene clusters (RKI6 and RKI7) and strains of serovars O45:H2 and O80:H2 showing multidrug resistance were detected. In conclusion, the implemented surveillance tools now allow to comprehensively define the population of clinical STEC strains including those associated with the severe disease manifestation HUS reaching a new surveillance level in Germany.

UK – Investigators confirm cheese firm’s link to deadly E. coli outbreak

Food Safety News

According to officials, the outbreak strain has been found at a farm that supplied the milk used to make unpasteurized cheese, which was linked to an E. coli outbreak in the UK.

In total, 36 confirmed and one probable Shiga toxin-producing E. coli (STEC) O145 infections have been reported, with 29 in England and eight in Scotland since late July 2023, with most falling ill in November. The last reported primary patient had symptom onset on Dec. 23, 2023.

Twenty patients were female, with ages of all cases ranging from 7 to 81. Of the 31 patients with available information, 20 had bloody diarrhea, 15 were admitted to the hospital, and four also attended the hospital for their symptoms. One person developed hemolytic uremic syndrome (HUS) and later died.

An investigation into the outbreak by the UK Health Security Agency (UKHSA), the local authority, Public Health Scotland, Food Standards Agency (FSA), Food Standards Scotland (FSS) and the Animal Plant Health Agency (APHA) is nearly completed.

UK – People hit by E.Coli outbreak ate Mrs Kirkham’s cheese in prepared meal in first class train carriage

Blog Preston

At least sixteen people who were infected in the E.Coli outbreak over Christmas ate ready meals containing unpasteurised cheese from a Preston business in the first class carriage of a train, Blog Preston has learned.

The investigation into E.Coli that led to dozens of people being infected, and one person dying, has also now concluded there is a ‘proven link’ between Mrs Kirkham’s Lancashire Cheese Ltd, which operates in Goosnargh, and the outbreak.

Mrs Kirkham’s was forced to issue a product recall on Christmas Eve 2023 over fears their unpasteurised cheese contained the harmful bacteria.

The Food Standards Agency has previously said that Mrs Kirkham’s acted ‘quickly and responsibly’ to take that action in December once the potential link had been established. Mrs Kirkham’s also received messages of support from the Specialist Cheesemakers’ Association and The Courtyard Dairy,