Category Archives: Research

USA – FDA – Food Defense Plan Builder

FDAucm340020

The Food Defense Plan Builder is a user-friendly software program designed to assist owners and operators of food facilities with developing personalized food defense plans for their facilities. This user-friendly tool harnesses existing FDA tools, guidance, and resources for food defense into one single application.

The Food Defense Plan Builder guides the user through the following sections:

  • Company Information
  • Broad Mitigation Strategies
  • Vulnerability Assessment
  • Focused Mitigation Strategies
  • Emergency Contacts
  • Action Plan
  • Supporting Documents

 

FDA – Reportable Food Registry Annual Report Third Annual Report: September 8, 2011 – September 7, 2012

FDA

This is the third annual report that measures our success in receiving early warning on problems with food and feed. The Reportable Food Registry (RFR) has already proven itself an invaluable tool to help prevent contaminated food from reaching the public.

By providing early warning about potential public-health risks from reportable foods, the Registry increases the speed with which the FDA, its state- and local-level partners, and industry can remove hazards from the marketplace.

The RFR data also is providing valuable data to help meet requirements under the Food Safety Modernization Act. For example, we can use the data to identify hazards associated with products for which we have not previously made such an association and thus identify foods for which preventive controls may be needed. The data are also being used to help target inspections, plan work, identify and prioritize risks and develop guidance for industry. The FDA will continue working closely with the food and feed industries to enhance this important and beneficial tool.
Michael R. Taylor Deputy Commissioner for Foods and Veterinary Medicine

FDA

Canada – Research Into E.coli O157 XL Outbreak 2012

Food Safety

The Panel members were appointed by the Governor in Council to undertake an independent review of the beef recall that occurred at XL Foods Inc.‘s plant at Brooks, Alberta between September and October 2012, and to submit a report to the Minister of Agriculture and Agri-Food.

We were asked to establish how the contamination occurred and, moreover, how the Canadian Food Inspection Agency (CFIA, or Agency), its food safety partners, and XL Foods Inc. responded to the situation. Lastly, we were tasked with providing recommendations that would address any findings or conclusions that we had made regarding these matters. We note that such findings or conclusions do not address civil or criminal liability; the standards that we are applying are not legal ones.

Over the course of several weeks, the Panel met with dozens of stakeholders. These included beef producers and processors, health authorities and academics, the retail industry, and union representatives for both the company and the Agency.

In this regard, we were left with a single overarching impression: everyone we interviewed expressed a keen desire to ensure that the food Canadians eat is safe. And they all wanted to be considered partners in the pursuit of that goal.

Research – Listeria monocytogenes Biofilm Formation

Science Direct

The foodborne pathogen Listeria monocytogenes has the ability to produce biofilms in food-processing environments and then contaminate food products, which is a major concern for food safety. The biofilm forming behaviour of 143 L. monocytogenes strains was determined in four different media that were rich, moderate or poor in nutrients at 12°C, 20°C, 30°C and 37°C. The biofilm formation was mostly influenced by temperature, resulting in decreased biofilm formation with decreasing temperature. Biofilm formation was enhanced in nutrient-poor medium rather than in nutrient-rich medium, and especially in nutrient-poor medium significantly enhanced biofilm production was observed early in biofilm maturation underlining the effect of medium on biofilm formation rate. Also serotype had a significant effect on biofilm formation and was influenced by medium used because strains from both serotype 1/2b and 1/2a formed more biofilm than serotype 4b strains in nutrient-rich medium at 20°C, 30°C and 37°C, whereas in nutrient-poor medium the biofilm production levels of serotype 1/2a and 4b strains were rather similar and lower than serotype 1/2b strains. The strains used originated from various origins, including dairy, meat, industrial environment, human and animal, and the level of biofilm formation was not significantly affected by the origin of isolation, irrespective of medium used and temperature tested. A linear model was used to correlate crystal violet staining of biofilm production to the number of viable cells within the biofilm. This showed that crystal violet staining was poorly correlated to the number of viable cells in nutrient-poor medium, and LIVE/DEAD staining and DNase I treatment revealed that this could be attributed to the presence of non-viable cells and extracellular DNA in the biofilm matrix. The significant impact of intrinsic and extrinsic factors on biofilm production of L. monocytogenes underlined that niche-specific features determine the levels of biofilm produced, and insights in biofilm formation characteristics will allow us to further optimize strategies to control the biofilm formation of L. monocytogenes.

 

Food Poisoning Bulletin – Hepatitis A – Killing

FPB

Hepatitis A is hard to kill.  The virus is normally transmitted when an infected person doesn’t wash his or her hands properly after going to the bathroom and then touches food or objects where it can live for a month or more.

USA – CDC Report on Listeria 2009-2011

CDCE.coli O157

This report details the epidemiology of invasive listeriosis, which often leads to bacteremia, meningitis, hospitalization, fetal loss, and death, and calls for actions that could protect the most vulnerable populations. Older adults and pregnant women, particularly pregnant Hispanic women, are at much higher risk than the population at large, as are persons with weakened immunity (2). Preventing infections in these populations can have substantial impact in averting these outcomes. Older adults and persons with weakened immunity, as well as infants and young children, are also prone to many other foodborne illnesses, including campylobacteriosis, salmonellosis, and Shiga toxin–producing E. coli infections (4). Accounting for underdiagnosis and underreporting, an estimated 1,662 cases of listeriosis occur each year (5). No progress in reducing the overall incidence of listeriosis has occurred in over a decade (3,4); renewed prevention efforts are needed from farm to table.

 

Research – Norovirus – Ozone – Hard Surface Disinfection

Ingenta ConnectNorwalk_Caspid

Human norovirus is the leading cause of epidemic gastroenteritis, especially in semiclosed settings such as daycares, nursing homes, hospitals, schools and on cruise ships. Outbreaks are often accompanied by contamination of environmental surfaces and commonly handled items. Surface disinfection of norovirus surrogates, feline calicivirus and murine norovirus, by 20 parts per million atmospheric ozone in a chamber maintaining 80% relative humidity was investigated. After treatment, neither virus could be detected on glass surfaces, but >5 log infectious virus was recovered from untreated controls. Ozone chambers used to decontaminate small, hand-contact items could be an important tool for controlling norovirus outbreaks

Ingenta Connect

Norovirus (NoV) infections are the leading cause of foodborne illness in the United States. Effective disinfection is important for controlling outbreaks caused by this highly infectious virus but can be difficult to achieve because NoV is very resistant to many common disinfection protocols. The inability of human NoV to replicate in tissue culture complicates NoV research, generally necessitating genome copy quantification, the use of surrogate viruses, or the use of other substitutes such as virus-like particles. To date, comprehensive comparisons among NoV surrogates and between surrogates and human NoV are missing, and it is not clear how best to extrapolate information from surrogate data. We conducted a systematic review and meta-analysis of comparisons of NoV surrogates with regard to their susceptibility to disinfection on hard surfaces or in suspension. Restricting our analysis to those studies in which two or more virus surrogates were compared allowed us to improve the signal-to-noise ratio in our analysis, similar to the epidemiological concept of matching. Using meta-analysis methods, our results indicate that hepatitis A virus, murine norovirus 1, and phage MS2 are significantly more resistant to disinfection than is feline calicivirus, but average differences in viral titer reduction appeared to be modest, 1.5 log PFU or less in all cases. None of the studies that compared surrogates and human NoV met our inclusion criteria, precluding a direct comparison between human NoV and NoV surrogates in this study. For all surrogates with sufficient data available to permit subgroup analyses, we detected strong evidence that the type of disinfectant impacted the relative susceptibility of the surrogates. Therefore, extrapolation of results between surrogates or from surrogates to human NoV must consider the type of disinfectant studied.

 

Research – Faster Salmonella ID – Mathematical Model Food Safety

Science CodexiStock_000008493122Small

A new approach may be able to reduce by more than half the time it takes health officials to identify Salmonella strains, according to researchers in Penn State’s College of Agricultural Sciences.

The finding may significantly speed up the response to many outbreaks of foodborne illness, allowing epidemiological investigators to identify the exact strains of Salmonella that make people sick and to more quickly find — and eliminate — the source of the disease.

Working in collaboration with Carol Sandt, a scientist with the Bureau of Laboratories, Division of Clinical Microbiology in the Pennsylvania Department of Health and Eija Trees, a microbiologist at the U.S. Centers for Disease Control and Prevention, Shariat used Salmonella samples supplied by the state health department. Results of the study were published online in May in the Journal of Clinical Microbiology.

“Compared to the current method being used nationally and internationally to subtype Salmonella, our approach is faster,” Shariat said. “The significance of that is you need to trace the source of an outbreak as quickly as you can before you start insisting on restaurant and farm closures. It is important to pinpoint the source of the bacteria — the quicker you do that the quicker you can respond to the disease outbreak.”

Ingenta Connect

This document describes the development of a tool to manage the risk of the transportation of cold food without temperature control. The tool uses predictions from ComBase predictor and builds on the 2009 U.S. Food and Drug Administration Model Food Code and supporting scientific data in the Food Code annex. I selected Salmonella spp. and Listeria monocytogenes as the organisms for risk management. Salmonella spp. were selected because they are associated with a wide variety of foods and grow rapidly at temperatures >17°C. L. monocytogenes was selected because it is frequently present in the food processing environment, it was used in the original analysis contained in the Food Code Annex, and it grows relatively rapidly at temperatures <17°C. The suitability of a variety of growth models under changing temperature conditions is largely supported by the published literature. The ComBase predictions under static temperature conditions were validated using 148 ComBase database observations for Salmonella spp. and L. monocytogenes in real foods. The times and temperature changes encompassed by ComBase Predictor models for Salmonella spp. and L. monocytogenes are consistent with published data on consumer food transport to the home from the grocery store and on representative foods from a wholesale cash and carry food service supplier collected as part of this project. The resulting model-based tool will be a useful aid to risk managers and customers of wholesale cash and carry food service suppliers, as well as to anyone interested in assessing and managing the risks posed by holding cold foods out of temperature control in supermarkets, delis, restaurants, cafeterias, and homes.

Research – Investigators Link Poultry Contamination on Farm and at Processing Plant

Eurek AlertimagesCAJOQ0KC

Researchers at the University of Georgia, Athens, have identified a strong link between the prevalence and load of certain food-borne pathogens on poultry farms, and later downstream at the processing plant. They report their findings in a manuscript published ahead of print in the journal Applied and Environmental Microbiology.

“This study suggests that reducing foodborne pathogen loads on broiler chicken farms would help to reduce pathogen loads at processing, and may ultimately help to reduce the risk of foodborne illness,” says Roy Berghaus, an author on the study. “This is important because most of our efforts towards reducing foodborne pathogens are currently focused on what happens during processing. Processing interventions are effective but they can only do so much.”

 

EU Dec 2012 – Increased Level of Official Controls on Imports of Certain Feed and Food of Non-Animal Origin

EU

The occurrence and relevance of food incidents notified through the Rapid Alert System for Food and Feed, the findings of audits to third countries carried out by the Food and Veterinary Office, as well as the quarterly reports on consignments of feed and food of non- animal origin submitted by Member States to the Commission in accordance with Article 15 of Regulation (EC) No 669/2009 indicate that the list should be amended.

(4)

In particular, for consignments of dried vine fruit from Afghanistan, watermelons from Brazil, strawberries from China, peas and beans from Kenya, mint from Morocco, watermelon seeds and derived products from Sierra Leone and certain herbs, spices and vegetables from Vietnam, the relevant sources of information indicate the emergence of new risks and/or a degree of non- compliance with the relevant safety requirements, thereby warranting the introduction of an increased level of official controls. Entries concerning those consignments should be therefore included in the list.