Category Archives: Microbiological Risk Assessment

USA – E. coli infections from unknown source under investigation in Alabama

Food Safety News

The Alabama Department of Public Health is investigating four cases of E. coli O157:H7 and two cases of Rotavirus in younger children in Northeastern Alabama. 

As of today the department had not reported what the possible sources of the pathogens might be. It is unknown if the sources involve foods or beverages, although food is the usual source of E. Coli infections.

The department regularly investigates clusters and outbreaks of communicable diseases as required by Notifiable Disease Rules in Alabama.

In 2021, ADPH investigated 113 cases of E. coli, shiga toxin-producing illness including O157:H7.

EU – 8 April update: ECDC/EFSA investigation into multi-country Salmonella outbreak continues

ECDC

The outbreak has been linked to a factory in Arlon. Belgian authorities suspended all activities, all products that were manufactured there will be recalled, and retailers are also asked to remove the products from their shelves.

An outbreak caused by monophasic Salmonella Typhimurium is rapidly evolving in eight EU/EEA countries and the United Kingdom (UK). As of 8 April 2022, 142 cases have been reported, mainly among children under 10 years old. The first case was identified in the UK on 7 January 2022. Since 17 February 2022, cases have also been identified elsewhere in Europe.

Geographical distribution of confirmed and probable cases of monophasic S. Typhimurium in the EU/EEA and the UK, as of 8 April 2022
 

The outbreak is characterised by an unusually high proportion of children being hospitalised, some with severe clinical symptoms such as bloody diarrhoea. Based on interviews with patients and initial analytical epidemiological studies, specific chocolate products have been identified as the likely route of infection. Affected cases have been identified through advanced molecular typing techniques. As this method of testing is not routinely performed in all countries, some cases may be undetected.

Product recalls have been launched in several countries to date, including BelgiumFranceGermanyIrelandLuxembourgNetherlandsNorway, and the UK, to prevent the consumption of products potentially contaminated with Salmonella. Further investigations are being conducted by public health and food safety authorities in countries where cases are reported, to identify the cause and the extent of the contamination, and to ensure contaminated products are not put on the market.

ECDC and EFSA are assessing the available data from these countries and preparing a rapid outbreak assessment to be published next week. Questions regarding ongoing product recalls should be addressed to national food safety authorities.

Number of confirmed and probable cases* with monophasic S. Typhimurium infection by country, EU/EEA and the UK, as of 8 April 2022

Country Confirmed cases Probable cases Total cases
Belgium 0 26 26
France 25 0 25
Germany 6 2 8
Ireland 10 0 10
Luxembourg 1 0 1
Netherlands 2 0 2
Norway 1 0 1
Sweden 4 0 4
Total EU/EEA 42 29 77
United Kingdom 65 0 65
Total 114 28 142

*According to the European outbreak case definition

USA – Food Safety Microsite

CDC

Food Poisoning Basics

Learn about the causes, signs, and symptoms of food poisoning and tips for how to prevent yourself and your family from getting sick.

Screenshot of PDF for how to protect yourself and your family from food poisoning

Research – Harmless or deadly? New study examines evolution of E. coli

UTS

A new study, published in Nature Communications, suggests genetic material from E. coli bacteria in farm animals could be contributing to the evolution of deadly strains of E. coli in humans.

Genetic material from E. coli bacteria in farm animals could be contributing to the evolution of deadly pandemic strains of E. coli in humans, new research shows.

E. coli usually live as harmless bacteria in the gastrointestinal tracts of birds and mammals, including humans. They also reside, independent of a host, in environments such as water and soil, and in food products including chicken and turkey meat, raw milk, beef, pork and mixed salad.

These bacteria can cause disease if they possess or acquire factors that allow them survive in areas of the human body outside the gut.

E. coli is the primary source of urinary tract infections, a common reason for hospital admissions. It can also lead to sepsis, which kills 11 million people globally each year, and meningitis, an infection that affects the brain and spinal cord.

Dr Cameron Reid, from the University of Technology Sydney, said the aim of the study, recently published in Nature Communications, was to better understand the evolution and genomic characteristics of an emerging strain of E. coli known as ST58.

Research – Biofilm Formation by Pathogenic Bacteria: Applying a Staphylococcus aureus Model to Appraise Potential Targets for Therapeutic Intervention

MDPI

Staphylococcus

Carried in the nasal passages by up to 30% of humans, Staphylococcus aureus is recognized to be a successful opportunistic pathogen. It is a frequent cause of infections of the upper respiratory tract, including sinusitis, and of the skin, typically abscesses, as well as of food poisoning and medical device contamination. The antimicrobial resistance of such, often chronic, health conditions is underpinned by the unique structure of bacterial biofilm, which is the focus of increasing research to try to overcome this serious public health challenge. Due to the protective barrier of an exopolysaccharide matrix, bacteria that are embedded within biofilm are highly resistant both to an infected individual’s immune response and to any treating antibiotics. An in-depth appraisal of the stepwise progression of biofilm formation by S. aureus, used as a model infection for all cases of bacterial antibiotic resistance, has enhanced understanding of this complicated microscopic structure and served to highlight possible intervention targets for both patient cure and community infection control. While antibiotic therapy offers a practical means of treatment and prevention, the most favorable results are achieved in combination with other methods. This review provides an overview of S. aureus biofilm development, outlines the current range of anti-biofilm agents that are used against each stage and summarizes their relative merits. View Full-Text

Research – Safety and Quality of Canned Sardines after Opening: A Shelf-Stability Study

MDPI

This study aimed to define the shelf life of canned sardines after opening to increase consumer awareness of their quality and safety and reduce food waste. For this purpose, canned sardines (Sardina pilchardus) packed with different sauces were opened and stored at 4 °C for 7 days. Microbiological, sensorial, physical and chemical stability was monitored daily by standard methodologies. Results show that the overall quality and safety are highly dependent on the sauce type. To preserve their full quality, sardines in brine and in vegetable oil should be consumed up to 1 day after opening, while sardines in tomato sauce were stable for up to 3 days, although none were considered nonedible up to the 7th day. Many parameters demonstrated statistical differences and correlations with storage, although they were not as decisive as sensory evaluation. This integrated approach should be adopted by the food industry and regulating authorities to provide information to consumers regarding the quality and safety of handled goods. View Full-Text

Research – Food Poisoning While Breastfeeding – What you need to know.

Food Poisoning News

Food poisoning can be a scary prospect, especially for breastfeeding mothers. But with a little knowledge, you can keep yourself and your baby safe. It is a common illness that can affect anyone. If you are breastfeeding and experience food poisoning, it is important to know what to do to protect your baby.

You can continue breastfeeding if you have food poisoning. In fact, the Centers for Disease Control and Prevention (CDC) even recommends that you continue breastfeeding if you have food poisoning.

The reason is that most germs that cause food poisoning are not passed from mother to baby through breast milk. If you are feeling ill, be sure to drink plenty of fluids (rehydration solutions like Pedialyte are best) so that you don’t get dehydrated. Dehydration can make you feel worse and can make it harder for your body to fight off any infection.

USA – How to Report Seafood-Related Toxin and Scombrotoxin Fish Poisoning Illnesses

FDA

To help FDA effectively investigate, remove unsafe seafood products from the market, and develop new prevention strategies, the FDA relies on illness reporting from public health officials and healthcare providers. While most foodborne outbreaks are tracked through the FDA’s Coordinated Outbreak Response and Evaluation (CORE) network, seafood-related illnesses caused by natural toxins have a unique reporting mechanism. This web page provides information on commonly occurring seafood-related illnesses and how to report them to the FDA.  To report an illness from raw bivalve molluscan shellfish, email the FDA at shellfishepi@fda.hhs.gov.

The FDA receives reports of illnesses associated with the consumption of specific types of fish. These illnesses may originate from the activity of certain bacteria, toxins produced by marine algae, or hazards inherent in the fish.

Commonly occurring illness:

Illness and reporting information for the commonly occurring illnesses are provided in each section. Contact the FDA with any questions or need for clarification of the illness or reporting.

In addition to the illnesses listed above, reporting of other less frequently occurring illnesses from natural toxins may be accomplished by emailing the FDA at Seafood.Illness@fda.hhs.gov.  Refer to Chapter 6 of the “Fish and Fishery Products Hazards and Controls Guidance” for a comprehensive list of natural toxin illnesses. To report illnesses related to miscellaneous natural toxin illnesses, please email FDA at Seafood.Illness@fda.hhs.gov.

The FDA works with first responders, physicians, and state and local health departments to investigate illnesses and outbreaks, manage them, and learn how to lessen future occurrences.

Research – A Multi-Skilled Mathematical Model of Bacterial Attachment in Initiation of Biofilms

MDPI

Biofilm of antibiotic resistant bacteria

The initial step of biofilm formation is bacteria attachment to biotic or abiotic surfaces and other bacteria through intra or interspecies interactions. Adhesion can be influenced by physicochemical conditions of the environment, such as iron. There is no available mathematical model of bacterial attachment giving realistic initiation rather than random adhesion. We describe a simple stochastic attachment model, from the simplest case in two dimensions with one bacterial species attaching on a homogeneous flat surface to more complex situations, with either several bacterial species, inhomogeneous or non-flat surfaces, or in three dimensions. The model depends on attachment probabilities (on the surface, laterally, or vertically on bacteria). Effects of each of these parameters were analyzed. This mathematical model is then applied to experimental oral microcolonies of Porphyromonas gingivalisStreptococcus gordonii, and Treponema denticola, either as mono-, two, or three species, under different iron concentrations. The model allows to characterize the adhesion of three bacterial species and explore the effect of iron on attachment. This model appears as a powerful tool for initial attachment analysis of bacterial species. It will enable further modeling of biofilm formation in later steps with biofilm initialization more relevant to real-life subgingival biofilms. View Full-Text

Research – Molecular Characterization of Staphylococcus aureus Strains Isolated from Mobile Phones

MDPI

Staph

The widespread use of mobile phones (MP) among healthcare personnel might be considered as an important source of contamination. One of the most pathogenic bacteria to humans is Staphylococcus aureus, which can be transmitted through the constant use of MP. Nevertheless, which specific type of strains are transmitted and which are their sources have not been sufficiently studied. The aim of this study is to determine the source of contamination of MP and characterize the corresponding genotypic and phenotypic properties of the strains found. Nose, pharynx, and MP samples were taken from a group of health science students. We were able to determinate the clonality of the isolated strains by pulsed-field gel electrophoresis (PFGE) and spa gene typing (spa-type). Adhesin and toxin genes were detected, and the capacity of biofilm formation was determined. Several of the MP exhibited strains of S. aureus present in the nose and/or pharynx of their owners. methicillin-susceptible Staphylococcus aureus (MSSA), hospital-acquired methicillin-resistant S. aureus (HA-MRSA), and community-acquired methicillin-resistant S. aureus (CA-MRSA) strains were found, which indicated a variety of genotypes. This study concludes that MP can be contaminated with the strains of S. aureus present in the nose and/or pharynx of the owners; these strains can be of different types and there is no dominant genotype. View Full-Text