Category Archives: Campylobacter

USA – FSIS Guideline for Controlling Campylobacter in Raw Poultry

FSIS USDA

GUIDELINE IDFSIS-GD-2021-0006
ISSUE DATEJuly 2021

Replaces: The Campylobacter part of the 2015 FSIS Guideline for Controlling Salmonella and Campylobacter in Raw Poultry

This guideline helps poultry establishments, including those that are small and very small, identify and implement pre- and post-harvest interventions to control Campylobacter as part of their HACCP system. Additionally, it helps poultry establishments utilizes microbial testing results to monitor the performance of the HACCP system and inform decision making. This guideline relates to 9 CFR 381, 416, and 417.

Disclaimer: The contents of this guidance document do not have the force and effect of law and are not meant to bind the public in any way. This document is intended only to provide clarity to the public regarding existing requirements under the law or agency policies.

Full Guideline

Research – The serious and long-term effects of foodborne illness

MSU

Campylobacter kswfoodworld

Many people think if they eat something “bad” they might spend some uncomfortable time in the restroom then go on with their lives in a day or two. Actually, foodborne illness can lead to chronic disease, permanent disability and even death. Here are some of the lesser-known facts about the long term effects of food borne pathogens.

Reactive arthritis, a type of joint inflammation that affects the knees, ankles or feet can develop after being exposed to Campylobacter jejuni  or Salmonella. Reactive arthritis usually lasts fewer than 6 months, but this condition may recur or become chronic arthritis. Campylobacter is found in raw and undercooked poultry, unpasteurized milk and contaminated water. Salmonella is also found in eggs, undercooked meat and poultry, and can be transferred to other foods through feces. Campylobacter infection afflicts millions of Americans annually and hospitalizes more than 10,000. Campylobacter is associated with Guillain-Barré syndrome (GBS). GBS patients can become permanently disabled and paralyzed; many require hospital care. Campylobacter also can trigger arthritis, heart infections and blood infections.

Foodborne illnesses caused by bacteria also increase the risk of developing irritable bowel syndrome (IBS). IBS is a disorder of unknown cause that is associated with abdominal pain, bloating, and diarrhea or constipation or both. There is no cure for IBS.

Children are the most likely to be infected and have the most serious complications from E. coli O157:H7. They can develop hemolytic uremic syndrome (HUS), HUS can lead to death, or in some cases t long-term or permanent health problems, including end-stage kidney disease, neurological complications, and insulin-dependent diabetes. Adults who had recovered from E. coli O157:H7 infections had increased risks of high blood pressure, kidney problems and cardiovascular disease. E. Coli is found in undercooked ground beef, unpasteurized (raw) milk and juice, soft cheeses made from raw milk, and raw fruits and vegetables (such as sprouts). It can also be found in contaminated water and feces of infected people.

Listeria monocytogenes infects thousands of Americans every year and has been associated with infections of the brain and spinal cord, resulting in serious neurological dysfunctions or death. Most reported cases occur in children under the age of 4, and about 1 in 5 people afflicted die as a result of the infection. In pregnant women, listeriosis can cause miscarriage, premature birth or stillbirth.

Listeriosis survivors often are left with serious neurological dysfunctions, including seizures, paralysis and impaired ability to see, hear, swallow or speak. Severe cases often result in partial to total impairment and can require life-long residential care with no possibility of work. Listeria is found in ready-to-eat deli meats and hot dogs, refrigerated pâtés or meat spreads, unpasteurized (raw) milk and dairy products, soft cheese made with unpasteurized milk, such as queso fresco, feta, brie, camembert, refrigerated smoked seafood and raw sprouts.

The long-term effects of foodborne disease are still not fully understood. New findings unfold as research is performed, but until then, taking foodborne illness seriously can go a long way in protecting health. This is another instance where prevention truly is the best medicine.

Denmark – WGS project on Campylobacter gives insights in Denmark

Food Safety News

CDC Campy

The study showed that roughly half of human infections belong to genetic clusters, almost one third of clinical isolates match a chicken source, and most large clusters can be linked to poultry by WGS.

Researchers hope the knowledge and awareness raised will lead to a decrease in the Danish chicken-associated cases of campylobacteriosis in coming years.

Denmark had 5,389 cases in 2019 and 33 percent of conventional chicken meat samples were positive for Campylobacter at slaughter. One third of infections are estimated to be travel-related.

Typing-based surveillance of Campylobacter infections in 2019 enabled detection of large clusters and matched them to retail chicken isolates to react to outbreaks. Surveillance was also able to detect prolonged or reappearing outbreaks to help earlier interventions, according to the study published in the journal Eurosurveillance.

Norway – Research – Risk ranking and source attribution of food- and waterborne pathogens for surveillance purposes – Toxoplasma the top risk!

VKM

Toxoplasma

Background
Providing risk managers with the information that they need for decision making is an important element in food-safety management. The present risk assessment was undertaken to establish a scientific basis that could be used to assist the Norwegian Food Safety Authority (NFSA) in implementing risk-based surveillance, monitoring, and control programmes for pathogens in food and water. The assessment approach used here consisted of two steps:(1) risk ranking of 20 selected pathogens based on the incidence and severity of their associated diseases following infection with the pathogens via food or water, and(2) a source attribution process aimed at identifying the main pathogen-food combinations that may pose a risk to human health for each of the ranked pathogens. We used an expert knowledge elicitation (EKE) procedure with a panel of nine experts, including all eight members of the Panel on Biological Hazards of the Norwegian Scientific Committee for Food and Environment (NSCFE) and one invited expert on food/water-borne viral infections.
Risk Ranking
The 20 pathogens selected for risk ranking were defined in the terms of reference (ToR) received from NFSA. We performed a multicriteria-based ranking of the pathogens in terms of their public health impact from food/water-borne transmission in Norway. The risk ranking utilized six criteria that estimated the incidence of food- and waterborne illness attributable to each pathogen, the severity of acute and chronic illness, the fraction of chronic illness, fatality rate, and the probability for future increased disease burden. For each pathogen, all criteria were scored by the expert panel members, and individual criterion scores were combined into an overall score for every pathogen. To achieve this, each criterion was weighted in terms of its relative importance, as judged by the expert panel. The overall scores so calculated were the basis for the ranking.
Source attribution
For each of the ranked pathogens, the subsequent source-attribution process aimed to identify the main food vehicles, reservoirs, and sources of infection for outbreak-related and sporadic cases of illness, the relative importance of food sources, and preventable risk factors in Norway. To achieve this, both microbiological and epidemiological data were scrutinized. These encompassed results from national surveillance and monitoring programmes, prevalence surveys, outbreak investigations, and research, including analytic epidemiological studies. When Norwegian data were sparse or absent, international reports and research were used.
Results
The six highest-ranked pathogens were, in descending order: Toxoplasma gondii, Campylobacter spp., Echinococcus multilocularis, enterohaemorrhagic E. coli (EHEC), Listeria monocytogenes, and non-typhoid Salmonella. It should be emphasized, however, that confidence intervals revealed considerable overlaps between the scores. The food vehicles associated with the pathogens varied widely. It is notable, however, that fresh produce was identified as being among the main food vehicles for 12 of the 20 pathogens, drinking water was associated with 8, and 5 were linked to raw milk or products thereof

UK – Major retailers below Campylobacter chicken limit; smaller shops test higher

Food Safety News

None of the top nine retailers in the United Kingdom reported Campylobacter in chicken test results near the FSA limit in the first three months of this year.

The Food Standards Agency (FSA) maximum acceptable level is 7 percent of birds with more than 1,000 colony forming units per gram (CFU/g) of Campylobacter.

Tesco was the supermarket that recorded the worst contaminated chicken results with 4 percent of 300 samples above 1,000 CFU/g in the first quarter of 2021 (1Q) which was down from 6 percent in 4Q 2020.

Sainsbury’s performed much better in the latest set of figures covering January to March with around 2 percent of chickens sampled above 1,000 CFU/g compared to 7 percent in 4Q 2020.

Asda reported 1.3 percent tested positive for the highest level of contamination in the latest quarter compared to 1.8 percent in the previous three months.

USA – Raw Milk Recall – Campylobacter

Food Poisoning Bulletin

An Eastern Idaho Campylobacter outbreak is associated with the consumption of raw milk, according to a notice posted on that agency’s Facebook page. Eastern Idaho Public Health is working in conjunction with the Idaho State Department of Agriculture and the Idaho Department of Health and Welfare to educate the public about the inherent risks of consuming unpasteurized dairy products.

UK – A survey of the levels of Campylobacter spp. contamination and prevalence of selected antimicrobial resistance determinants in fresh whole UK-produced chilled chickens at retail sale (non-major retailers)

Click to access campylobacter-contamination-in-fresh-whole-uk-produced-chilled-chickens-at-retail-sale-year-5-2018-2019.pdf

Research – Poultry study points to genes linked to food bug – Campylobacter.

Roslin

Campylobacter kswfoodworld

Variation in the response of chickens to Campylobacter helps identify key genes that may provide resistance to infection.

Research has identified genes in chickens that could offer resistance to harmful bacteria commonly found in poultry and could inform ways to limit the risk of associated food poisoning in people.

The study, led by a team from the Roslin institute, has identified a large number of genes in chicken guts that may determine whether the birds are resistant to Campylobacter.

The insights could inform research towards breeding chickens that are less likely to carry Campylobacter bacteria, and so limit the risk to poultry consumers.

Research – Application of peroxyacetic acid for decontamination of raw poultry products and comparison to other commonly used chemical antimicrobial interventions – A Review

Journal of Food Protection

Poultry remains one of the top food commodities responsible for foodborne illness in the U.S., despite poultry industry efforts since the inception of HACCP to reduce the burden of foodborne illness implicating poultry products. The appropriate use of antimicrobial compounds during processing of raw poultry can help minimize this risk. Currently, peroxyacetic acid (PAA) is the most popular antimicrobial in the poultry industry, displacing chlorine compounds and others. The aim of this review was to compare the effectiveness of PAA to that of other antimicrobials for the decontamination of raw poultry carcasses and parts. Twenty-six articles were found that compared PAA to over 20 different antimicrobials, applied as spray or immersion treatments for different exposure times and concentrations. The most common comparisons were to chlorine compounds (17 articles), to lactic acid (LA) compounds (5 articles) and to cetylpyridinium chloride (CPC, 6 articles). Studies measured effectiveness by reductions in native flora or inoculated bacteria, usually Salmonella or Campylobacter . PAA was found to be more effective than chlorine under most conditions studied. Effectiveness of PAA was higher or comparable to that of LA and CPC depending on product and treatment conditions. Overall, the results of primary literature studies support the popularity of PAA as an effective intervention against pathogenic bacteria during poultry processing.

Research – Whole genome sequencing data used for surveillance of Campylobacter infections: detection of a large continuous outbreak, Denmark, 2019

Eurosurveillance

CDC Campy

Human campylobacteriosis is the most commonly reported zoonotic disease in Europe, with 246,571 reported cases in the European Union (EU) in 2018 [1].  infections are predominantly food-borne, with poultry as the primary source. However, other transmission routes are known, such as bathing, drinking contaminated water or direct contact with animals. In food samples, the highest occurrence of  was detected in fresh chicken meat (37.5% of samples tested) [1]. In Denmark, we had 5,389 registered human cases in 2019 (incidence: 93/100,000 inhabitants) and 33% of conventional chicken meat samples were positive for  at slaughter [2]. Of note, one third of the human infections diagnosed in Denmark are estimated to be travel-related [3].

Efforts to identify the specific source of  infection in humans are rarely made in Denmark or other countries. Therefore, relevant information for targeted public health actions to prevent  infections often does not exist. For decades, surveillance of other food-borne pathogens, especially  and  with high-discriminatory typing methods has proved to be a powerful tool for outbreak detection and investigations as well as for following trends and emergence of epidemic strains. Similar typing-based surveillance for  has not been widely used and generally has not been very useful for the decision-making process on mitigating efforts by the public health and food safety authorities. The high diversity of  isolates and the general assumption that most  infections are sporadic are plausible explanations.

We have previously shown that, based on whole genome sequencing (WGS) data of  isolates in 2015–17, we could identify numerous small outbreak-like clusters and, in many instances, genetically link them to concurrent animal and food isolates [4]. A large fraction of all 774 clinical isolates (27%) could be genetically linked to broilers or chicken meat, whereas only a few clinical isolates (2%) could be genetically linked to cattle isolates. A Danish case–control study conducted in the same period pointed at several food sources of campylobacteriosis among children and young adults, including consumption of chicken meat, minced beef, and fresh strawberries [5]. Therefore, in addition to sampling of chicken meat, the Danish Veterinary and Food Administration (DVFA) initiated sampling and analysis for  in several other food sources that were identified by the case–control study to obtain knowledge on the impact of these sources.

In our 2015–17 study, a comparison of human isolates to food and animal isolates was done retrospectively and therefore no specific public health actions were taken. To evaluate the value of a prospective and continuous WGS-based surveillance system for  in Denmark, we initiated WGS of isolates from human cases and retail food samples as well as the concurrent analysis of these cross-sector data. Here, we report the first year of surveillance (2019) and show that integrated WGS-based surveillance of  in humans and food sources can identify correlations between the occurrence of specific strains in chicken meat and in human infections. The surveillance was also able to detect prolonged or reappearing outbreaks, which allows for specific interventions to control  in the food production chain and thereby prevent human infections.