Researchers at the University of Texas (UT) Southwestern Medical Center have discovered how foodborne pathogen Vibrio parahaemolyticus infects people after eating raw or undercooked shellfish. The findings could lead to new ways to treat illness caused by the enteric bacteria.
The study provides the first visual evidence of how a gut bacterial pathogen uses an “assembly method” to build syringe-like structures to inject toxins into intestinal cells, giving a new view of how enteric bacteria, when exposed to bile acids, efficiently respond and build a virulence system.