Salmonella enterica is a leading worldwide cause of foodborne human illnesses (WHO, 2015).
Salmonella isolates can be differentiated into serotypes according to the Kauffmann-White classification based on their flagellar (H) and somatic antigens (Grimont P. & Weill FX, 2007) or using genome-based serotyping approaches (Banerji S. et al ., 2020 ).
Among the> 2500 referenced serotypes (Ibrahim GM and Morin PM, 2018), Enteritidis and Typhimurium have proven to be both consistent contaminants along the food chain but more importantly as prominent isolates from diseases in humans (EFSA & ECDC, 2021).
These two serotypes are indeed particularly adapted to hostile environments such as farm animals or food industries’ environments and ultimately, human bodies. Their chromosomal or plasmid-borne virulence and regulatory factors often associated to antimicrobial resistance determinants (Cadel-six S. et al ., 2021) confer upon them striking fitness for survival and spread (Chen RA et al., 2019; Huang X. et al. al ., 2019; Guillén, S. et al ., 2021).