Category Archives: Colistin Resistant

Research – Global Emergence of Colistin-Resistant Escherichia coli in Food Chains and Associated Food Safety Implications: A Review

Journal of Food Protection


Antimicrobial resistance in bacteria represents one of the most important challenges for public health worldwide. Human infections from antimicrobial-resistant bacteria can be transmitted from person to person, via the environment (especially in the hospital environment), or via handling or eating contaminated foods. Colistin is well known as a last-resort antibiotic for the treatment of human infections; a recent study performed in the People’s Republic of China has revealed that colistin resistance is also conferred by the plasmid-mediated mcr-1 gene in Escherichia coli. After that discovery, further plasmid-mediated, colistin resistance genes have been detected. However, to date, only reports on E. coli carrying the mcr-1 gene (E. coli mcr-1+) in foodstuff are available. E. coli mcr-1+ has been isolated from food of animal origin and vegetables; this discovery has opened a debate among food safety experts. This review aims to provide a critical overview of the currently available scientific literature on the presence of the plasmid-mediated, colistin resistance gene E. coli mcr-1 in foodstuffs, focusing on the main implications and future perspectives for food safety.

  • Antimicrobial resistance in the food chain: a One Health perspective.

  • Escherichia coli carries the mcr-1 gene in food-producing animals.

  • Escherichia coli carrying the mcr-1 gene in food from animals and vegetables is significant.

UK- Scotland – Levels of antimicrobial resistant E. coli in UK retail meat remain low


CDC E.coli


The Food Standards Agency (FSA) have published the Year Three results of an EU survey commissioned to assess the frequency of certain types of antimicrobial resistant (AMR) E. coli in raw UK retail pork and beef.

Year Three of the survey was carried out between January and December 2017 during which 314 beef and 310 pork samples were purchased from retail premises in England, Scotland, Wales and Northern Ireland and tested for specific types of AMR E. coli.

The survey generates baseline data on certain types of AMR E. coli found in retail meat in the UK, which informs assessment of the risks found, and steps needed be taken, in order to reduce exposure to AMR.

Overall, the results showed that less than 1% of the samples were positive for ESBL or AmpC E. coli, which are specific types of AMR. These results are similar to what was found in Year One of the survey. However, one beef sample was found to be contaminated with an E. coli containing the mcr-1 gene, which confers resistance to the antibiotic colistin.

[Source: FSA, 13 November 2018.…]

Research – Multi-drug-resistant (MDR), colistin-resistant E. coli bacteria pervasive in Vietnam village

Outbreak News Today Ecoli Istock

A new study has found that the majority of residents in a rural village of Vietnam harbored multi-drug-resistant (MDR), colistin-resistant E. coli bacteria. Colistin is typically used as a last-resort treatment when there are no other therapy options available. The research is presented at ASM Microbe, the annual meeting of the American Society for Microbiology, held from June 7th to June 11th in Atlanta, GA.

“These results revealed the dissemination of MDR colistin-resistant E. coli, harboring the colistin-resistant mobile gene mcr among commensal bacteria of residents, in a rural community in Vietnam,” said Yoshimasa Yamamoto, Ph.D., Osaka University, Osaka, Japan, presenting author on the study.

The colistin-resistant bacteria were detected in 71.4% of the residents in Nguyen Xa village in Vietnam. All the colistin-resistant isolates were identified as E. coli.