Research – Hepatitis A outbreak with the concurrence of Salmonella Typhi and Salmonella Poona infection in children of urban Vellore, south India – 2019

IJID Online

Background: Outbreaks of Hepatitis A virus (HAV) infection continue to be reported from India, that have transitioned from hyper-to-intermediate endemicity. Hepatitis A and Salmonella sp. share similar routes of transmission and may co-infect individuals at risk. We report here an outbreak of hepatitis A with concomitant Salmonellosis from an urban settlement of Vellore in south India between July and August 2019.

Our findings highlight that Hepatitis A infection can present as sporadic outbreaks in communities with sub-standard water and sewage systems, along with the co-infection of other enteric infections such as invasive Salmonellosis. Thus, population-based surveillance for Hepatitis A is required in India, to identify populations and geographical regions at risk, and thereby potentially plan implementation strategies for Hepatitis A vaccination.

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