HACCPEUROPA – Full Article
Norovirus causes more than half of all food-borne illnesses in the United States, and is the second greatest source of reported food borne illness outbreaks in the European Union. A norovirus is a small virus that contains RNA and is surrounded by a protein coating. By sequencing the RNA, scientists have discovered that there are many different types of norovirus. Originally, strains were named based on the city in which they were first identified. Thus, one common strain used to be called Norwalk virus. Based on genetic typing, we now know that there are at least 25 different strains of norovirus that affect humans.
A recent study found that grape seed extract could reduce the infectivity of Norovirus surrogates.
Researchers from Ghent University, Belgium have shown that grape seed extract does so by denaturing the capsid protein, which is the coat of the virus, thereby disabling the virus.
In the study, the researchers observed that under treatment with grape seed extract, at low doses, the spherically-shaped murine (mouse) norovirus-1 coat proteins clumped, and showed obvious deformation and inflation. At higher doses, the researchers saw no coat proteins, only protein debris. This provides evidence that grape seed extract could effectively damage the norovirus capsid protein, which could reduce viral binding ability and infectivity accordingly.
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