Vaccinating Chickens – Campylobacter

Eurek Alert

A vaccine could be developed to prevent Campylobacter being carried in chickens. This approach could drastically cut the number of cases of food poisoning, saving the UK economy millions each year, says an American scientist presenting his work at the Society for General Microbiology’s Spring Conference in Dublin.

Scientists at Washington State University are studying the maternal antibodies that are passed from hens to their chicks. “These antibodies protect chicks from becoming colonized by Campylobacter in the first week of life,” explained Professor Michael Konkel who is leading the research. “Our group has now identified the bacterial molecules that these antibodies attack, which has given us a starting point for a vaccine against Campylobacter,” he said. “We have already found that chickens injected with these specific molecules – found on the surface of Campylobacter jejuni – produce antibodies against the bacterium. This response partially protects them from colonization.”

A vaccine could be a powerful weapon to help control food-borne illness. “Preventing contamination of poultry at slaughter has not been effective at reducing illness in humans. It has been shown that about 65% of chickens on retail sale in the UK are contaminated with Campylobacter,” explained Professor Konkel. “Ideally, the best way to prevent contamination is to stop chickens on the farm from becoming colonized with this microorganism in the first place, which could be achieved by vaccination. Our goal within the next 6 months is to test a vaccine for chickens that will reduce Campylobacter colonization levels. There’s still a long way to go, but I’m confident our lab and others are moving in the right direction.”

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