Research -Disarming a pathogen’s ability to cause disease

mBiosphere

The anaerobic, Gram-positive Clostridium difficile is a big problem. It causes rampant diarrhea and tissue necrosis, with more than 150,000 annual cases in the United States alone. Many of the disease manifestations of C. difficile are mediated by two exotoxins that C. difficile produces: TcdA and TcdB. Researchers have long been working at toxin inhibition as an approach to disarm C. difficile and improve treatment, and new research in Clinical and Vaccine Immunology shows promise in blocking toxin activity in vivo.

http://mbioblog.asm.org/mbiosphere/2016/07/disarming-a-pathogens-ability-to-cause-disease.html

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