Research -New technology traces resistance gene quickly – Colistin

Technical University of Denmark

A new resistance gene has been found in coli bacteria among pigs, broiler meat and humans in China. Bacteria with the same resistance gene have now also been found in Denmark, according to a new Danish study. The National Food Institute, Technical University of Denmark, and Statens Serum Institut have been able to quickly create an overview of the situation in Denmark because many bacteria have had their DNA-profile mapped with the help of whole genome sequencing.

The National Food Institute is working to develop global databases in order to further the intelligent use of whole genome sequencing data.

This work takes place in the network Global Microbial Identifier and the EU project COMPARE. Both have the aim of creating a global system of databases for whole genome sequencing. These databases will be used to identify and diagnose disease-causing microorganisms and infectious diseases. They will also make it possible to compare data with information on outbreaks and emerging disease-causing microorganisms.

The National Food Institute also performs the role of WHO Collaborating Centre and EU reference laboratory for antimicrobial resistance. As such, the reference laboratory is planning in agreement with the European Commission to examine the prevalence of mcr-1 in cooperation with national veterinary and food laboratories in the EU.

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